AUGMENTIN 375MG DESCRIPTION
AUGMENTIN 375MG TABLET is a combination of Amoxicillin and Clavulanic Acid which belongs to the group of medicines called Antibiotics. It is used to treat bacterial infections including middle ear & sinus infections, respiratory tract infections, genital tract infections, urinary tract infections, skin & soft tissue infections such as dental infections, bone & joint infections, septic abortion and abdominal infections. The symptoms of bacterial infection include fever, difficulty in breathing, pus formation, and pain.
AUGMENTIN 375MG TABLET is not recommended for use if you have liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate. Before taking this medicine, inform your doctor if you are suffering from a hepatic impairment, liver disease, renal impairment, kidney disease, glandular fever, or are unable to pass water properly.
AUGMENTIN 375MG TABLET should be used with caution in pregnant and breastfeeding women only if it is considered necessary. It should be used with caution in children (aged below 12 years) and elderly patients (above 50 years). Consult your doctor before taking AUGMENTIN 375MG TABLET.
The common side effects associated with the use of AUGMENTIN 375MG TABLET are diarrhoea, thrush (fungal infection in the vagina, skin folds, or mouth), nausea, and vomiting. Contact your doctor immediately if any of the symptoms worsen.
USES OF AUGMENTIN 375MG TABLET
- Treats bacterial infection
HOW AUGMENTIN 375MG TABLET WORKS
AUGMENTIN 375MG TABLET helps in treating bacterial infection where amoxicillin is a penicillin that works by inhibiting the enzymes that help in the synthesis of the integral structural component of the bacterial cell wall whereas clavulanic acid is a beta-lactam (structurally related to penicillin) that works by inactivating an enzyme, namely beta-lactamase, thereby preventing the inactivation of amoxicillin.
DIRECTIONS FOR USE
Film-coated tablets:
Take AUGMENTIN 375MG TABLET as advised by your physician. Swallow the tablet with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Dispersible tablets:
Take AUGMENTIN 375MG TABLET as advised by your physician. Place the tablet in the mouth, let it dissolve, and then swallow. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Powder for oral suspension (in sachets):
Take AUGMENTIN 375MG TABLET as advised by your physician. Open the sachet, mix the contents thoroughly in a glass of water, and swallow the mixture immediately. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF AUGMENTIN 375MG TABLET
COMMON
- Diarrhoea
- Thrush (fungal infection in the vagina, skin folds, or mouth)
- Nausea
- Vomiting
UNCOMMON
- Skin rash
- Itching
- Raised itchy rash (hives)
- Indigestion
- Dizziness
- Headache
RARE
- Erythema multiforme (a skin rash that looks like small targets)
- Reversible leucopoenia including neutropenia (deficiency of white blood cells)
- Reversible thrombocytopenia (deficiency of blood platelets)
Stop taking AUGMENTIN 375MG TABLET and contact your doctor if you experience any of the following side effects:
- Signs of allergic reactions on the skin such as skin rash
- Signs of vasculitis (inflammation of blood vessels) such as raised red or purple spots on the skin
- Signs of allergic reactions such as fever, joint pain, swollen glands in the neck, armpit or groin
- Signs of angioedema such as swelling on the face or mouth resulting in difficulty in breathing, or collapse
- Inflammation of the liver (hepatitis)
- Jaundice
- Inflammation of kidney tubes
- Prolongation of blood clotting time
- Convulsions
- Black tongue with hairy look
- Staining of teeth
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhoea and consult your doctor if the symptom gets worse.
Nausea and vomiting:
Try to take AUGMENTIN 375MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
WARNING & PRECAUTIONS
PREGNANCY
AUGMENTIN 375MG TABLET should be used with caution in pregnant women only if it is considered clearly necessary. Consult your doctor before taking AUGMENTIN 375MG TABLET.
BREASTFEEDING
AUGMENTIN 375MG TABLET should be used with caution in breastfeeding women. Consult your doctor before taking AUGMENTIN 375MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate machines while taking if you feel unwell.
KIDNEY
AUGMENTIN 375MG TABLET should be used with caution in patients with renal impairment or kidney problems. Consult your doctor before taking AUGMENTIN 375MG TABLET.
LIVER
AUGMENTIN 375MG TABLET is not recommended for use if you have if you ever had liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate. It should be used with caution in patients with hepatic impairment or liver problems. Consult your doctor before taking AUGMENTIN 375MG TABLET.
ALLERGY
Do not take AUGMENTIN 375MG TABLET if you are allergic to amoxicillin, clavulanic acid, penicillin, any antibiotic, or any other ingredients of this medicine. Consult your doctor before taking AUGMENTIN 375MG TABLET.
OTHERS
Before taking AUGMENTIN 375MG TABLET, inform your doctor if you:
- Have glandular fever
- Are unable to pass water properly
Use in Paediatrics:
AUGMENTIN 375MG TABLET should be used with caution in children (below 12 years). Consult your doctor before taking AUGMENTIN 375MG TABLET.
Use in Geriatrics:
AUGMENTIN 375MG TABLET should be used with caution in elderly patients (above 50 years). Consult your doctor before taking AUGMENTIN 375MG TABLET.
INTERACTIONS
A. Drug-Drug Interactions
Before taking AUGMENTIN 375MG TABLET, inform your doctor, if you are taking any of the following medicine:
- Allopurinol, probenecid (medicine used to treat gout)
- Warfarin (medicine used to delay blood clotting)
- Methotrexate (medicine used to treat rheumatic diseases or certain cancers)
- Mycophenolate mofetil (a medicine used to prevent the organ rejection after organ transplant)
- Contraceptives (medicines used to prevent conception)
MORE INFORMATION
- Keep the medicine out of reach of children
- Store AUGMENTIN 375MG TABLET at a temperature not exceeding 30°C